Biology Crossword Puzzle
STEM crossword with 15 biology terms
Biology Crossword Puzzle
STEM crossword with 15 biology terms
Across
- 2.The control center of a cell
- 3.Built from amino acids; essential for structure and function
- 5.Cell division producing two identical daughter cells
- 8.Single-celled organisms found everywhere on Earth
- 10.Change in species over time through natural selection
- 11.Thin flexible layer surrounding a cell
Down
- 1.Basic unit of all living things
- 4.Biological catalyst that speeds up reactions
- 6.Water movement across a semipermeable membrane
- 7.Nerve cell that transmits signals
- 9.Community of organisms and their shared environment
- 12.Natural home of an organism
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What is a Crossword?
A STEM crossword uses subject-area vocabulary as the answer words. Each clue defines a term from the featured field — biology, physics, chemistry, math, or computer science.
How to solve it
Start with clues whose answers you know for certain — filled letters unlock adjacent clues. Use the crossing letters to confirm uncertain answers.
Who is this for?
STEM crosswords are perfect for science and math classrooms, tutoring sessions, gifted programs, and anyone who loves both puzzles and learning.
About this puzzle
Free printable biology crossword puzzle — 15 science terms for students. STEM-themed, instant PDF download.
- Difficulty: Medium
- Format: US Letter PDF with answer key
- Free to download, print, and use
- Commercial use allowed for KDP publishers
Step-by-step: solving the Biology Crossword Puzzle
- Print the PDF. Download and print the free STEM crossword PDF. The grid and clue list are on page one.
- Start with confident clues. Read every across and down clue. Fill in the answers you know for certain — these unlock crossing letters.
- Use intersections to confirm. When you're not sure about a clue, check the crossing letters from a confirmed answer. Spelling is a strong constraint.
- Verify with the answer key. Compare the finished grid to the answer key on the second page.